Meet Velico at upcoming conferences across North America and Europe and learn more about our FrontlineODP™ Spray Dried Plasma Manufacturing System. America’s Blood Centers (ABC) Annual Meeting, Tucson, Arizona (Mar 9–12) | DMHD – Defense Medical & Health Delivery Conference, London, UK (Mar 24–25)

Spray Dried Plasma

FrontlineODP™ On Demand Plasma

Our Spray dried plasma unit the FrontlineODP™ (On Demand Plasma) is designed for rapid rehydration, intended to support the management of traumatic hemorrhage in situations where conventional plasma is unavailable or impractical. This includes pre-hospital transfusions, rural and austere healthcare settings, and military applications.

A spray dried plasma solution will potentially allow for new methods of blood product distribution throughout the EMT community. The potential longevity of Spray Dried Plasma means that emergency vehicles may be able to carry this product for longer than whole blood or other alternatives without replenishing as often.

In addition, as spray dried plasma is being designed to be stored in ambient conditions, it has the potential to save more lives, especially where emergency vehicles do not have appropriate refrigerated facilities but could provide ambient controlled temperature storage conditions.

FrontODP™ Unique Features

Rehydration in 2.5 minutes
Comparable Factor Activity
Ultra Lightweight PVC Bag
24 Months Shelf Life

The FrontlineODP™ unit is easily rehydrated in two and a half minutes with 200ml of sterile water (SWFI), making it practical in prehospital and hospital settings (i.e. rural) where fresh plasma is unavailable.

Watch how Spray Dried Plasma the FrontlineODP™ Rehydrates
Step 1
Step 2
Step 3
Pretreatment Process

Plasma is pre-treated in a sterile, non-pyrogenic, single-use Plasma Pretreatment Container. The pre-treated plasma is then transferred, to the Plasma Drying Chamber.

Pretreatment Process

Plasma is pre-treated in a sterile, non-pyrogenic, single-use Plasma Pretreatment Container. The pre-treated plasma is then transferred, to the Plasma Drying Chamber.

Pretreatment Process

Plasma is pre-treated in a sterile, non-pyrogenic, single-use Plasma Pretreatment Container. The pre-treated plasma is then transferred, to the Plasma Drying Chamber.

Why its needed

Severe bleeding is the leading cause of preventable death after traumatic injury. When minutes matter, early plasma administration has been shown to save lives.*

Despite this, 30–40% of deaths from bleeding are considered preventable. In the United States alone, more than 30,000 people die each year from bleeding that might have been stopped. Globally, that number rises to over 100,000 preventable deaths every year.*

The need for plasma in emergencies is not new. During World War II, over 10 million units of dried plasma were produced to support lifesaving care. Today, global production capacity is less than 30,000 units annually —
far below what is needed to protect both civilian and
military patients.

30-40%
of deaths from bleeding are considered preventable
100,000+
preventable deaths every year*

Conventional Plasma FFP/PF24

  • Cold Chain requirements for frozen storage and transport
  • Long thawing times (30 minutes)
  • High breakage rates

Lyophilized Plasma

  • Glass bottles – bulky, not flexible/ compressible
  • Prone to breakage
  • Weeks to manufacture and release
There is a clear and urgent need for portable, easily stored and easy to use plasma to bring lifesaving treatment closer to the point of injury.
#PlasmaEverywhere
*Sperry JL, et al. Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock. NEJM. 2018;379(4):315-326.

Our Solution

Efficient. Scalable. Reliable.

In just over 30 minutes, the FrontlineODP Spray Dried Plasma System transforms one unit of plasma into a shelf stable, ready to use spray dried plasma product. With a single Frontline ODP System, you can produce up to 9,000 units annually.

Human Plasma
Liquid Plasma
Pretreatment Solution
Liquid Plasma
Plasma Drying Chamber (PDC) (Cleanroom in a bag)
VeliDryer
3000-9000 Units Per Year (1-3 x 8hr Shifts)
VeliSealer
3000-9000 Units Per Year (1-3 x 8hr Shifts)
FrontlineODP™
Transfusion ready in 2.5 minutes

Key Features of the FrontlineODP™ Manufacturing System

Decentralized manufacturing
Integrates into blood bank labs
Designed for ease of use and operation
Scalable Production Capacity

Watch our innovative FrontlineODP™ system at work

Strategic Partnerships

Developing strategic relationships is key to the adoption and integration of the FontlineODP™ Manufacturing System into civilian and military organisations.
Watch some of our partners in action
South Texas Blood & Tissue join Velico’s Blood Center Education Program
UK Army & NHSBT Dry Plasma Development Contract Awarded to Velico

Production Models

The FrontlineODP™ Spray Dried Plasma Manufacturing System is being designed for easy integration in blood center component laboratories. Decentralized production by blood centers will aim to take advantage of blood component manufacturing expertise
and product supply chains, from established volunteer blood donor bases to end user distribution including emergency logistics channels.

Decentralized production sets the stage for local spray dried plasma self-sufficiency and national emergency preparedness including civilian, government and military collaboration for strategic stockpiles and readiness for major mass casualty events.

Velico

  • Cold Chain requirements for frozen storage and transport
  • Long thawing times (30 minutes)
  • High breakage rates

Blood Centers

  • Cold Chain requirements for frozen storage and transport
  • Long thawing times (30 minutes)
  • High breakage rates

Distributors

  • Cold Chain requirements for frozen storage and transport
  • Long thawing times (30 minutes)
  • High breakage rates

End Users

  • Cold Chain requirements for frozen storage and transport
  • Long thawing times (30 minutes)
  • High breakage rates

Velipod

At Velico, innovation means bringing lifesaving plasma production closer to where it’s needed most. Building on our FrontlineODP™ spray-dried plasma technology, we developed the veliPod™, a modular, self-contained plasma production lab engineered for rapid deployment and scalable capacity.

Want to learn more?

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